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A Dual-Role of Gu-4 in Suppressing HMGB1 Secretion and Blocking HMGB1 Pro-Inflammatory Activity during Inflammation

BACKGROUND: High mobility group box 1(HMGB1) was first recognized as a nuclear protein that increased the chromatin remodeling and regulates transcription of many genes. In recent years, HMGB1 has been identified as a critical “late” pro-inflammatory mediator due to its unique secretion pattern and...

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Detalles Bibliográficos
Autores principales:	Zhou, HuiTing, Ji, XueMei, Wu, Yun, Xuan, Ju, Qi, ZhiLin, Shen, Lei, Lan, Lei, Li, Qing, Yin, ZhiMin, Li, ZhongJun, Zhao, ZhiHui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945943/ https://www.ncbi.nlm.nih.gov/pubmed/24603876 http://dx.doi.org/10.1371/journal.pone.0089634

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