Structure and mutagenesis of the DNA modification-dependent restriction endonuclease AspBHI

The modification-dependent restriction endonuclease AspBHI recognizes 5-methylcytosine (5mC) in the double-strand DNA sequence context of (C/T)(C/G)(5mC)N(C/G) (N = any nucleotide) and cleaves the two strands a fixed distance (N(12)/N(16)) 3′ to the modified cytosine. We determined the crystal struc...

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Detalles Bibliográficos
Autores principales: Horton, John R., Nugent, Rebecca L., Li, Andrew, Mabuchi, Megumu Yamada, Fomenkov, Alexey, Cohen-Karni, Devora, Griggs, Rose M., Zhang, Xing, Wilson, Geoffrey G., Zheng, Yu, Xu, Shuang-yong, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946040/
https://www.ncbi.nlm.nih.gov/pubmed/24604015
http://dx.doi.org/10.1038/srep04246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946040/
https://www.ncbi.nlm.nih.gov/pubmed/24604015
http://dx.doi.org/10.1038/srep04246

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