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Structure and mutagenesis of the DNA modification-dependent restriction endonuclease AspBHI
The modification-dependent restriction endonuclease AspBHI recognizes 5-methylcytosine (5mC) in the double-strand DNA sequence context of (C/T)(C/G)(5mC)N(C/G) (N = any nucleotide) and cleaves the two strands a fixed distance (N(12)/N(16)) 3′ to the modified cytosine. We determined the crystal struc...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946040/ https://www.ncbi.nlm.nih.gov/pubmed/24604015 http://dx.doi.org/10.1038/srep04246 |