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Manipulation of valve composition to elucidate the role of collagen in aortic valve calcification

BACKGROUND: Extracellular matrix (ECM) disarray is found in calcific aortic valvular disease (CAVD), yet much remains to be learned about the role of individual ECM components in valvular interstitial cell (VIC) function and dysfunction. Previous clinical analyses have shown that calcification is as...

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Detalles Bibliográficos
Autores principales: Rodriguez, Karien J, Piechura, Laura M, Porras, Ana M, Masters, Kristyn S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946110/
https://www.ncbi.nlm.nih.gov/pubmed/24581344
http://dx.doi.org/10.1186/1471-2261-14-29