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Manipulation of valve composition to elucidate the role of collagen in aortic valve calcification
BACKGROUND: Extracellular matrix (ECM) disarray is found in calcific aortic valvular disease (CAVD), yet much remains to be learned about the role of individual ECM components in valvular interstitial cell (VIC) function and dysfunction. Previous clinical analyses have shown that calcification is as...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946110/ https://www.ncbi.nlm.nih.gov/pubmed/24581344 http://dx.doi.org/10.1186/1471-2261-14-29 |