RAS mutations in early age leukaemia modulated by NQO1 rs1800566 (C609T) are associated with second-hand smoking exposures

BACKGROUND: Deregulation of the MAPK genes signalling caused by somatic mutations have been implied in leukaemia pathogenesis, including RAS mutation (RAS(mut)) in acute myeloid leukaemia (AML), which has been associated with intra-uterine chemical exposures. A case-case study was conducted in order...

Descripción completa

Detalles Bibliográficos
Autores principales: Andrade, Francianne Gomes, Furtado-Silva, Juliana Montibeller, Gonçalves, Bruno Alves de Aguiar, Thuler, Luiz Claudio Santos, Barbosa, Thayana Conceição, Emerenciano, Mariana, Siqueira, André, Pombo-de-Oliveira, Maria S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946262/
https://www.ncbi.nlm.nih.gov/pubmed/24571676
http://dx.doi.org/10.1186/1471-2407-14-133

Ejemplares similares

Ejemplares similares