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Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder
BACKGROUND: The 39,X(Y*)O mouse, which lacks the orthologues of the ADHD and autism candidate genes STS (steroid sulphatase) and ASMT (acetylserotonin O-methyltransferase), exhibits behavioural phenotypes relevant to developmental disorders. The neurobiology underlying these phenotypes is unclear, a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946266/ https://www.ncbi.nlm.nih.gov/pubmed/24602487 http://dx.doi.org/10.1186/2040-2392-5-21 |