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CYP 450 2C19 polymorphisms in Indian patients with coronary artery disease

BACKGROUND: Dual antiplatelet therapy is the cornerstone in the management of acute coronary syndromes (ACS) and prevention of stent thrombosis (ST). Genetic polymorphisms in CYP2C19 gene involved in hepatic activation of clopidogrel leads to clopidogrel non-responsiveness and may influence clinical...

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Detalles Bibliográficos
Autores principales: Shetkar, Sudhir S., Ramakrishnan, Sivasubramanian, Seth, Sandeep, Chandna, Puneet, Verma, Sunil K., Bhargava, Balram, Bahl, Vinay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946470/
https://www.ncbi.nlm.nih.gov/pubmed/24581091
http://dx.doi.org/10.1016/j.ihj.2013.10.001