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Independent Risk Factors for Urological Complications after Deceased Donor Kidney Transplantation

Urological complications after kidney transplantation are mostly related to the ureteroneocystostomy, often requiring interventions with additional costs, morbidity and mortality. Our aim was to assess risk factors for urological complications in deceased donor kidney transplantation. Between Januar...

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Autores principales: Slagt, Inez K. B., IJzermans, Jan N. M., Visser, Laurents J., Weimar, Willem, Roodnat, Joke I., Terkivatan, Türkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946700/
https://www.ncbi.nlm.nih.gov/pubmed/24608797
http://dx.doi.org/10.1371/journal.pone.0091211
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author Slagt, Inez K. B.
IJzermans, Jan N. M.
Visser, Laurents J.
Weimar, Willem
Roodnat, Joke I.
Terkivatan, Türkan
author_facet Slagt, Inez K. B.
IJzermans, Jan N. M.
Visser, Laurents J.
Weimar, Willem
Roodnat, Joke I.
Terkivatan, Türkan
author_sort Slagt, Inez K. B.
collection PubMed
description Urological complications after kidney transplantation are mostly related to the ureteroneocystostomy, often requiring interventions with additional costs, morbidity and mortality. Our aim was to assess risk factors for urological complications in deceased donor kidney transplantation. Between January 2000 and December 2011, 566 kidney transplantations were performed with deceased donor kidneys. Recipients were divided in a group with, and a group without urological complications, defined as the need for a percutaneous nephrostomy catheter or surgical revision of the ureteroneocystostomy. Univariate and multivariate analyses were performed. Univariate analysis showed increased number of male donors (p = 0.041), male recipients (p = 0.002), pre-emptively transplanted recipients (p = 0.007), and arterial reconstructions (p = 0.004) in the group with urological complications. Less urological complications occurred in recipients on hemodialysis (p = 0.005). More overall surgical interventions (p<0.001), surgical site infections (p = 0.042), urinary tract infections (p<0.001) and lymphoceles (p<0.001) occurred in the group with urological complications. Multivariate analysis showed that male recipients (p = 0.010) and arterial reconstructions (p = 0.019) were independent risk factors. No difference was found between both groups in patient or graft survival. In conclusion, recipient male gender and arterial reconstruction are independent risk factors for urological complications after deceased donor kidney transplantation. Nevertheless, graft and recipient survival is not different between both groups.
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spelling pubmed-39467002014-03-10 Independent Risk Factors for Urological Complications after Deceased Donor Kidney Transplantation Slagt, Inez K. B. IJzermans, Jan N. M. Visser, Laurents J. Weimar, Willem Roodnat, Joke I. Terkivatan, Türkan PLoS One Research Article Urological complications after kidney transplantation are mostly related to the ureteroneocystostomy, often requiring interventions with additional costs, morbidity and mortality. Our aim was to assess risk factors for urological complications in deceased donor kidney transplantation. Between January 2000 and December 2011, 566 kidney transplantations were performed with deceased donor kidneys. Recipients were divided in a group with, and a group without urological complications, defined as the need for a percutaneous nephrostomy catheter or surgical revision of the ureteroneocystostomy. Univariate and multivariate analyses were performed. Univariate analysis showed increased number of male donors (p = 0.041), male recipients (p = 0.002), pre-emptively transplanted recipients (p = 0.007), and arterial reconstructions (p = 0.004) in the group with urological complications. Less urological complications occurred in recipients on hemodialysis (p = 0.005). More overall surgical interventions (p<0.001), surgical site infections (p = 0.042), urinary tract infections (p<0.001) and lymphoceles (p<0.001) occurred in the group with urological complications. Multivariate analysis showed that male recipients (p = 0.010) and arterial reconstructions (p = 0.019) were independent risk factors. No difference was found between both groups in patient or graft survival. In conclusion, recipient male gender and arterial reconstruction are independent risk factors for urological complications after deceased donor kidney transplantation. Nevertheless, graft and recipient survival is not different between both groups. Public Library of Science 2014-03-07 /pmc/articles/PMC3946700/ /pubmed/24608797 http://dx.doi.org/10.1371/journal.pone.0091211 Text en © 2014 Slagt et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Slagt, Inez K. B.
IJzermans, Jan N. M.
Visser, Laurents J.
Weimar, Willem
Roodnat, Joke I.
Terkivatan, Türkan
Independent Risk Factors for Urological Complications after Deceased Donor Kidney Transplantation
title Independent Risk Factors for Urological Complications after Deceased Donor Kidney Transplantation
title_full Independent Risk Factors for Urological Complications after Deceased Donor Kidney Transplantation
title_fullStr Independent Risk Factors for Urological Complications after Deceased Donor Kidney Transplantation
title_full_unstemmed Independent Risk Factors for Urological Complications after Deceased Donor Kidney Transplantation
title_short Independent Risk Factors for Urological Complications after Deceased Donor Kidney Transplantation
title_sort independent risk factors for urological complications after deceased donor kidney transplantation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946700/
https://www.ncbi.nlm.nih.gov/pubmed/24608797
http://dx.doi.org/10.1371/journal.pone.0091211
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