High Frequency of Fusion Transcripts Involving TCF7L2 in Colorectal Cancer: Novel Fusion Partner and Splice Variants

VTI1A-TCF7L2 was reported as a recurrent fusion gene in colorectal cancer (CRC), found to be expressed in three out of 97 primary cancers, and one cell line, NCI-H508, where a genomic deletion joins the two genes [1]. To investigate this fusion further, we analyzed high-throughput DNA and RNA sequen...

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Detalles Bibliográficos
Autores principales: Nome, Torfinn, Hoff, Andreas M., Bakken, Anne Cathrine, Rognum, Torleiv O., Nesbakken, Arild, Skotheim, Rolf I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946716/
https://www.ncbi.nlm.nih.gov/pubmed/24608966
http://dx.doi.org/10.1371/journal.pone.0091264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946716/
https://www.ncbi.nlm.nih.gov/pubmed/24608966
http://dx.doi.org/10.1371/journal.pone.0091264

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