Immunological and Virological Mechanisms of Vaccine-Mediated Protection Against SIV and HIV

A major challenge for the development of a highly effective AIDS vaccine is the identification of mechanisms of protective immunity. To address this question, we used a non-human primate challenge model with simian immunodeficiency virus (SIV). We show that antibodies to the SIV Envelope are necessa...

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Detalles Bibliográficos
Autores principales: Roederer, Mario, Keele, Brandon F., Schmidt, Stephen D., Mason, Rosemarie D., Welles, Hugh C., Fischer, Will, Labranche, Celia, Foulds, Kathryn E., Louder, Mark K., Yang, Zhi-Yong, Todd, John-Paul M., Buzby, Adam P., Mach, Linh V., Shen, Ling, Seaton, Kelly E., Ward, Brandy M., Bailer, Robert T., Gottardo, Raphael, Gu, Wenjuan, Ferrari, Guido, Alam, S. Munir, Denny, Thomas N., Montefiori, David C., Tomaras, Georgia D., Korber, Bette T., Nason, Martha C., Seder, Robert A., Koup, Richard A., Letvin, Norman L., Rao, Srinivas S., Nabel, Gary J., Mascola, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946913/
https://www.ncbi.nlm.nih.gov/pubmed/24352234
http://dx.doi.org/10.1038/nature12893

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