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Untethered micro-robotic coding of three-dimensional material composition

Complex functional materials with three-dimensional micro- or nano-scale dynamic compositional features are prevalent in nature. However, the generation of three-dimensional functional materials composed of both soft and rigid microstructures, each programmed by shape and composition, is still an un...

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Detalles Bibliográficos
Autores principales: Tasoglu, S., Diller, E., Guven, S., Sitti, M., Demirci, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947548/
https://www.ncbi.nlm.nih.gov/pubmed/24469115
http://dx.doi.org/10.1038/ncomms4124
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author Tasoglu, S.
Diller, E.
Guven, S.
Sitti, M.
Demirci, U.
author_facet Tasoglu, S.
Diller, E.
Guven, S.
Sitti, M.
Demirci, U.
author_sort Tasoglu, S.
collection PubMed
description Complex functional materials with three-dimensional micro- or nano-scale dynamic compositional features are prevalent in nature. However, the generation of three-dimensional functional materials composed of both soft and rigid microstructures, each programmed by shape and composition, is still an unsolved challenge. Herein, we describe a method to code complex materials in three-dimensions with tunable structural, morphological, and chemical features using an untethered magnetic micro-robot remotely controlled by magnetic fields. This strategy allows the micro-robot to be introduced to arbitrary microfluidic environments for remote two- and three-dimensional manipulation. We demonstrate the coding of soft hydrogels, rigid copper bars, polystyrene beads, and silicon chiplets into three-dimensional heterogeneous structures. We also use coded microstructures for bottom-up tissue engineering by generating cell-encapsulating constructs.
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spelling pubmed-39475482014-07-28 Untethered micro-robotic coding of three-dimensional material composition Tasoglu, S. Diller, E. Guven, S. Sitti, M. Demirci, U. Nat Commun Article Complex functional materials with three-dimensional micro- or nano-scale dynamic compositional features are prevalent in nature. However, the generation of three-dimensional functional materials composed of both soft and rigid microstructures, each programmed by shape and composition, is still an unsolved challenge. Herein, we describe a method to code complex materials in three-dimensions with tunable structural, morphological, and chemical features using an untethered magnetic micro-robot remotely controlled by magnetic fields. This strategy allows the micro-robot to be introduced to arbitrary microfluidic environments for remote two- and three-dimensional manipulation. We demonstrate the coding of soft hydrogels, rigid copper bars, polystyrene beads, and silicon chiplets into three-dimensional heterogeneous structures. We also use coded microstructures for bottom-up tissue engineering by generating cell-encapsulating constructs. 2014 /pmc/articles/PMC3947548/ /pubmed/24469115 http://dx.doi.org/10.1038/ncomms4124 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Tasoglu, S.
Diller, E.
Guven, S.
Sitti, M.
Demirci, U.
Untethered micro-robotic coding of three-dimensional material composition
title Untethered micro-robotic coding of three-dimensional material composition
title_full Untethered micro-robotic coding of three-dimensional material composition
title_fullStr Untethered micro-robotic coding of three-dimensional material composition
title_full_unstemmed Untethered micro-robotic coding of three-dimensional material composition
title_short Untethered micro-robotic coding of three-dimensional material composition
title_sort untethered micro-robotic coding of three-dimensional material composition
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947548/
https://www.ncbi.nlm.nih.gov/pubmed/24469115
http://dx.doi.org/10.1038/ncomms4124
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