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Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis

Background. Vitiligo has important clinical and social consequences particularly in the pigmented skin. The present study was conducted to assess the differences in clinicoepidemiological presentation of vitiligo in males and females and to understand the factors associated with spread of vitiligo i...

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Autores principales: Patil, Sharmila, Gautam, Manjyot, Nadkarni, Nitin, Saboo, Neha, Godse, Kiran, Setia, Maninder Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947737/
https://www.ncbi.nlm.nih.gov/pubmed/24696786
http://dx.doi.org/10.1155/2014/186197
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author Patil, Sharmila
Gautam, Manjyot
Nadkarni, Nitin
Saboo, Neha
Godse, Kiran
Setia, Maninder Singh
author_facet Patil, Sharmila
Gautam, Manjyot
Nadkarni, Nitin
Saboo, Neha
Godse, Kiran
Setia, Maninder Singh
author_sort Patil, Sharmila
collection PubMed
description Background. Vitiligo has important clinical and social consequences particularly in the pigmented skin. The present study was conducted to assess the differences in clinicoepidemiological presentation of vitiligo in males and females and to understand the factors associated with spread of vitiligo in them. Methods. This is a cross-sectional analysis of secondary clinical data of 168 vitiligo patients at a tertiary medical centre at Navi Mumbai. We used logistic regression models to estimate the association between gender and clinical characteristics of vitiligo and to evaluate the factors associated with spread of vitiligo. Results. There were no significant differences between the mean ages of males and females; however, males reported a longer duration of disease (6.9 (10.4) years) compared with females (4.9 (7.4) years). Males were significantly more likely to report a family history of vitiligo compared with females (adjusted OR (aOR): 16.87, 95% CI: 2.16 to 131.69). Even though females were more likely to report spread of lesions, the association was not statistically significant (OR: 1.21, 95% CI: 0.62 to 2.36). Discussion. The differences in the clinical presentations between genders highlight the need to understand the different factors (possibly genetic) that may play a part in the pathogenesis of this multifactorial disease in males and females.
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spelling pubmed-39477372014-04-02 Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis Patil, Sharmila Gautam, Manjyot Nadkarni, Nitin Saboo, Neha Godse, Kiran Setia, Maninder Singh ISRN Dermatol Research Article Background. Vitiligo has important clinical and social consequences particularly in the pigmented skin. The present study was conducted to assess the differences in clinicoepidemiological presentation of vitiligo in males and females and to understand the factors associated with spread of vitiligo in them. Methods. This is a cross-sectional analysis of secondary clinical data of 168 vitiligo patients at a tertiary medical centre at Navi Mumbai. We used logistic regression models to estimate the association between gender and clinical characteristics of vitiligo and to evaluate the factors associated with spread of vitiligo. Results. There were no significant differences between the mean ages of males and females; however, males reported a longer duration of disease (6.9 (10.4) years) compared with females (4.9 (7.4) years). Males were significantly more likely to report a family history of vitiligo compared with females (adjusted OR (aOR): 16.87, 95% CI: 2.16 to 131.69). Even though females were more likely to report spread of lesions, the association was not statistically significant (OR: 1.21, 95% CI: 0.62 to 2.36). Discussion. The differences in the clinical presentations between genders highlight the need to understand the different factors (possibly genetic) that may play a part in the pathogenesis of this multifactorial disease in males and females. Hindawi Publishing Corporation 2014-02-13 /pmc/articles/PMC3947737/ /pubmed/24696786 http://dx.doi.org/10.1155/2014/186197 Text en Copyright © 2014 Sharmila Patil et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Patil, Sharmila
Gautam, Manjyot
Nadkarni, Nitin
Saboo, Neha
Godse, Kiran
Setia, Maninder Singh
Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis
title Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis
title_full Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis
title_fullStr Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis
title_full_unstemmed Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis
title_short Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis
title_sort gender differences in clinicoepidemiological features of vitiligo: a cross-sectional analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947737/
https://www.ncbi.nlm.nih.gov/pubmed/24696786
http://dx.doi.org/10.1155/2014/186197
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