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Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis
Background. Vitiligo has important clinical and social consequences particularly in the pigmented skin. The present study was conducted to assess the differences in clinicoepidemiological presentation of vitiligo in males and females and to understand the factors associated with spread of vitiligo i...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947737/ https://www.ncbi.nlm.nih.gov/pubmed/24696786 http://dx.doi.org/10.1155/2014/186197 |
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author | Patil, Sharmila Gautam, Manjyot Nadkarni, Nitin Saboo, Neha Godse, Kiran Setia, Maninder Singh |
author_facet | Patil, Sharmila Gautam, Manjyot Nadkarni, Nitin Saboo, Neha Godse, Kiran Setia, Maninder Singh |
author_sort | Patil, Sharmila |
collection | PubMed |
description | Background. Vitiligo has important clinical and social consequences particularly in the pigmented skin. The present study was conducted to assess the differences in clinicoepidemiological presentation of vitiligo in males and females and to understand the factors associated with spread of vitiligo in them. Methods. This is a cross-sectional analysis of secondary clinical data of 168 vitiligo patients at a tertiary medical centre at Navi Mumbai. We used logistic regression models to estimate the association between gender and clinical characteristics of vitiligo and to evaluate the factors associated with spread of vitiligo. Results. There were no significant differences between the mean ages of males and females; however, males reported a longer duration of disease (6.9 (10.4) years) compared with females (4.9 (7.4) years). Males were significantly more likely to report a family history of vitiligo compared with females (adjusted OR (aOR): 16.87, 95% CI: 2.16 to 131.69). Even though females were more likely to report spread of lesions, the association was not statistically significant (OR: 1.21, 95% CI: 0.62 to 2.36). Discussion. The differences in the clinical presentations between genders highlight the need to understand the different factors (possibly genetic) that may play a part in the pathogenesis of this multifactorial disease in males and females. |
format | Online Article Text |
id | pubmed-3947737 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39477372014-04-02 Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis Patil, Sharmila Gautam, Manjyot Nadkarni, Nitin Saboo, Neha Godse, Kiran Setia, Maninder Singh ISRN Dermatol Research Article Background. Vitiligo has important clinical and social consequences particularly in the pigmented skin. The present study was conducted to assess the differences in clinicoepidemiological presentation of vitiligo in males and females and to understand the factors associated with spread of vitiligo in them. Methods. This is a cross-sectional analysis of secondary clinical data of 168 vitiligo patients at a tertiary medical centre at Navi Mumbai. We used logistic regression models to estimate the association between gender and clinical characteristics of vitiligo and to evaluate the factors associated with spread of vitiligo. Results. There were no significant differences between the mean ages of males and females; however, males reported a longer duration of disease (6.9 (10.4) years) compared with females (4.9 (7.4) years). Males were significantly more likely to report a family history of vitiligo compared with females (adjusted OR (aOR): 16.87, 95% CI: 2.16 to 131.69). Even though females were more likely to report spread of lesions, the association was not statistically significant (OR: 1.21, 95% CI: 0.62 to 2.36). Discussion. The differences in the clinical presentations between genders highlight the need to understand the different factors (possibly genetic) that may play a part in the pathogenesis of this multifactorial disease in males and females. Hindawi Publishing Corporation 2014-02-13 /pmc/articles/PMC3947737/ /pubmed/24696786 http://dx.doi.org/10.1155/2014/186197 Text en Copyright © 2014 Sharmila Patil et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Patil, Sharmila Gautam, Manjyot Nadkarni, Nitin Saboo, Neha Godse, Kiran Setia, Maninder Singh Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis |
title | Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis |
title_full | Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis |
title_fullStr | Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis |
title_full_unstemmed | Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis |
title_short | Gender Differences in Clinicoepidemiological Features of Vitiligo: A Cross-Sectional Analysis |
title_sort | gender differences in clinicoepidemiological features of vitiligo: a cross-sectional analysis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947737/ https://www.ncbi.nlm.nih.gov/pubmed/24696786 http://dx.doi.org/10.1155/2014/186197 |
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