ARID5B polymorphism confers an increased risk to acquire specific MLL rearrangements in early childhood leukemia

BACKGROUND: Acute leukemia in early age (EAL) is characterized by acquired genetic alterations such as MLL rearrangements (MLL-r). The aim of this case-controlled study was to investigate whether single nucleotide polymorphisms (SNPs) of IKZF1, ARID5B, and CEBPE could be related to the onset of EAL...

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Detalles Bibliográficos
Autores principales: Emerenciano, Mariana, Barbosa, Thayana Conceição, Lopes, Bruno Almeida, Blunck, Caroline Barbieri, Faro, Alessandra, Andrade, Camilla, Meyer, Claus, Marschalek, Rolf, Pombo-de-Oliveira, Maria S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948138/
https://www.ncbi.nlm.nih.gov/pubmed/24564228
http://dx.doi.org/10.1186/1471-2407-14-127

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