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Expression of nucleoside-metabolizing enzymes in myelodysplastic syndromes and modulation of response to azacitidine
The nucleoside analog azacitidine (AZA) is used in the treatment of myelodysplastic syndromes (MDS), but 30–40% of patients fail to respond or relapse after treatment. Hence, to identify new molecular alterations that allow for identification of patients unlikely to respond to AZA could impact the u...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948159/ https://www.ncbi.nlm.nih.gov/pubmed/24192812 http://dx.doi.org/10.1038/leu.2013.330 |