Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1

We identify an Arabidopsis pyridoxal-phosphate (PLP)-dependent aminotransferase, VAS1, whose loss-of-function simultaneously increases levels of the phytohormone auxin and the ethylene precursor 1-aminocyclopropane-1-carboxylate (ACC). VAS1 uses the ethylene biosynthetic intermediate Met as an amino...

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Autores principales: Zheng, Zuyu, Guo, Yongxia, Novák, Ondřej, Dai, Xinhua, Zhao, Yunde, Ljung, Karin, Noel, Joseph P., Chory, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948326/
https://www.ncbi.nlm.nih.gov/pubmed/23377040
http://dx.doi.org/10.1038/nchembio.1178
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author Zheng, Zuyu
Guo, Yongxia
Novák, Ondřej
Dai, Xinhua
Zhao, Yunde
Ljung, Karin
Noel, Joseph P.
Chory, Joanne
author_facet Zheng, Zuyu
Guo, Yongxia
Novák, Ondřej
Dai, Xinhua
Zhao, Yunde
Ljung, Karin
Noel, Joseph P.
Chory, Joanne
author_sort Zheng, Zuyu
collection PubMed
description We identify an Arabidopsis pyridoxal-phosphate (PLP)-dependent aminotransferase, VAS1, whose loss-of-function simultaneously increases levels of the phytohormone auxin and the ethylene precursor 1-aminocyclopropane-1-carboxylate (ACC). VAS1 uses the ethylene biosynthetic intermediate Met as an amino donor and the auxin biosynthetic intermediate, indole-3-pyruvic acid (3-IPA) as an amino acceptor to produce L-Trp and 2-oxo-4-methylthiobutyric acid (KMBA). Our data indicate that VAS1 serves key roles in coordinating the levels of these two vital hormones.
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spelling pubmed-39483262014-03-10 Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1 Zheng, Zuyu Guo, Yongxia Novák, Ondřej Dai, Xinhua Zhao, Yunde Ljung, Karin Noel, Joseph P. Chory, Joanne Nat Chem Biol Article We identify an Arabidopsis pyridoxal-phosphate (PLP)-dependent aminotransferase, VAS1, whose loss-of-function simultaneously increases levels of the phytohormone auxin and the ethylene precursor 1-aminocyclopropane-1-carboxylate (ACC). VAS1 uses the ethylene biosynthetic intermediate Met as an amino donor and the auxin biosynthetic intermediate, indole-3-pyruvic acid (3-IPA) as an amino acceptor to produce L-Trp and 2-oxo-4-methylthiobutyric acid (KMBA). Our data indicate that VAS1 serves key roles in coordinating the levels of these two vital hormones. 2013-02-03 2013-04 /pmc/articles/PMC3948326/ /pubmed/23377040 http://dx.doi.org/10.1038/nchembio.1178 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Zheng, Zuyu
Guo, Yongxia
Novák, Ondřej
Dai, Xinhua
Zhao, Yunde
Ljung, Karin
Noel, Joseph P.
Chory, Joanne
Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1
title Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1
title_full Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1
title_fullStr Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1
title_full_unstemmed Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1
title_short Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1
title_sort coordination of auxin and ethylene biosynthesis by the aminotransferase vas1
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948326/
https://www.ncbi.nlm.nih.gov/pubmed/23377040
http://dx.doi.org/10.1038/nchembio.1178
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