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Evolution of the Retroviral Restriction Gene Fv1: Inhibition of Non-MLV Retroviruses
Fv1 is the prototypic restriction factor that protects against infection by the murine leukemia virus (MLV). It was first identified in cells that were derived from laboratory mice and was found to be homologous to the gag gene of an endogenous retrovirus (ERV). To understand the evolution of the ho...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948346/ https://www.ncbi.nlm.nih.gov/pubmed/24603659 http://dx.doi.org/10.1371/journal.ppat.1003968 |