Accumulation of GABAergic Neurons, Causing a Focal Ambient GABA Gradient, and Downregulation of KCC2 Are Induced During Microgyrus Formation in a Mouse Model of Polymicrogyria

Although focal cortical malformations are considered neuronal migration disorders, their formation mechanisms remain unknown. We addressed how the γ-aminobutyric acid (GABA)ergic system affects the GABAergic and glutamatergic neuronal migration underlying such malformations. A focal freeze-lesion (F...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Tianying, Kumada, Tatsuro, Morishima, Toshitaka, Iwata, Satomi, Kaneko, Takeshi, Yanagawa, Yuchio, Yoshida, Sachiko, Fukuda, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948493/
https://www.ncbi.nlm.nih.gov/pubmed/23246779
http://dx.doi.org/10.1093/cercor/bhs375

Ejemplares similares

Ejemplares similares