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Plant natural products as an anti-lipid droplets accumulation agent

Recently people often suffer from unhealthy energy metabolism balance as they tend to take more energy than required. Normally, excess energy taken in is converted into triglyceride and stored in adipocyte as lipid droplets. Recent studies have suggested that irregular accumulation of triglyceride i...

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Detalles Bibliográficos
Autores principales: Wong, Chin Piow, Kaneda, Toshio, Morita, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948524/
https://www.ncbi.nlm.nih.gov/pubmed/24550097
http://dx.doi.org/10.1007/s11418-014-0822-3
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author Wong, Chin Piow
Kaneda, Toshio
Morita, Hiroshi
author_facet Wong, Chin Piow
Kaneda, Toshio
Morita, Hiroshi
author_sort Wong, Chin Piow
collection PubMed
description Recently people often suffer from unhealthy energy metabolism balance as they tend to take more energy than required. Normally, excess energy taken in is converted into triglyceride and stored in adipocyte as lipid droplets. Recent studies have suggested that irregular accumulation of triglyceride in adipocyte might be a cause of many metabolic diseases. Thus, the awareness of the detrimental effects on health of excessive lipid droplets accumulation (LDA) has urged the development or finding of drugs to counter this effect, including those from botanical origins. This review summarized recent progress in this field from the viewpoint of crude drug studies with references to their anti-LDA activity. Possible mechanisms involved in their anti-LDA effect and isolations of the relevant bioactive compounds were also discussed.
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spelling pubmed-39485242014-03-14 Plant natural products as an anti-lipid droplets accumulation agent Wong, Chin Piow Kaneda, Toshio Morita, Hiroshi J Nat Med Review Recently people often suffer from unhealthy energy metabolism balance as they tend to take more energy than required. Normally, excess energy taken in is converted into triglyceride and stored in adipocyte as lipid droplets. Recent studies have suggested that irregular accumulation of triglyceride in adipocyte might be a cause of many metabolic diseases. Thus, the awareness of the detrimental effects on health of excessive lipid droplets accumulation (LDA) has urged the development or finding of drugs to counter this effect, including those from botanical origins. This review summarized recent progress in this field from the viewpoint of crude drug studies with references to their anti-LDA activity. Possible mechanisms involved in their anti-LDA effect and isolations of the relevant bioactive compounds were also discussed. Springer Japan 2014-02-19 2014 /pmc/articles/PMC3948524/ /pubmed/24550097 http://dx.doi.org/10.1007/s11418-014-0822-3 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/2.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Review
Wong, Chin Piow
Kaneda, Toshio
Morita, Hiroshi
Plant natural products as an anti-lipid droplets accumulation agent
title Plant natural products as an anti-lipid droplets accumulation agent
title_full Plant natural products as an anti-lipid droplets accumulation agent
title_fullStr Plant natural products as an anti-lipid droplets accumulation agent
title_full_unstemmed Plant natural products as an anti-lipid droplets accumulation agent
title_short Plant natural products as an anti-lipid droplets accumulation agent
title_sort plant natural products as an anti-lipid droplets accumulation agent
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948524/
https://www.ncbi.nlm.nih.gov/pubmed/24550097
http://dx.doi.org/10.1007/s11418-014-0822-3
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