Prokaryotic Soluble Overexpression and Purification of Bioactive Human Growth Hormone by Fusion to Thioredoxin, Maltose Binding Protein, and Protein Disulfide Isomerase

Human growth hormone (hGH) is synthesized by somatotroph cells of the anterior pituitary gland and induces cell proliferation and growth. This protein has been approved for the treatment of various conditions, including hGH deficiency, chronic renal failure, and Turner syndrome. Efficient production...

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Detalles Bibliográficos
Autores principales: Nguyen, Minh Tan, Koo, Bon-Kyung, Thi Vu, Thu Trang, Song, Jung-A, Chong, Seon-Ha, Jeong, Boram, Ryu, Han-Bong, Moh, Sang-Hyun, Choe, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948679/
https://www.ncbi.nlm.nih.gov/pubmed/24614134
http://dx.doi.org/10.1371/journal.pone.0089038

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