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Pharmacological Inhibition of Cochlear Mitochondrial Respiratory Chain Induces Secondary Inflammation in the Lateral Wall: A Potential Therapeutic Target for Sensorineural Hearing Loss
Cochlear lateral wall has recently been reported as a common site of inflammation, yet precise molecular mechanisms of the inflammatory responses remain elucidated. The present study examined the inflammatory responses in the lateral wall following acute mitochondrial dysfunction induced by a mitoch...
Autores principales: | Fujioka, Masato, Okamoto, Yasuhide, Shinden, Seiichi, Okano, Hirotaka James, Okano, Hideyuki, Ogawa, Kaoru, Matsunaga, Tatsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948682/ https://www.ncbi.nlm.nih.gov/pubmed/24614528 http://dx.doi.org/10.1371/journal.pone.0090089 |
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