Approaches to Improve the Oral Bioavailability and Effects of Novel Anticancer Drugs Berberine and Betulinic Acid

BACKGROUND: The poor bioavailability of Berberine (BBR) and Betulinic acid (BA) limits the development of these promising anticancer agents for clinical use. In the current study, BBR and BA in spray dried (SD) mucoadhesive microparticle formulations were prepared. METHODS: A patented dual channel s...

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Detalles Bibliográficos
Autores principales: Godugu, Chandraiah, Patel, Apurva R., Doddapaneni, Ravi, Somagoni, Jaganmohan, Singh, Mandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948684/
https://www.ncbi.nlm.nih.gov/pubmed/24614362
http://dx.doi.org/10.1371/journal.pone.0089919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948684/
https://www.ncbi.nlm.nih.gov/pubmed/24614362
http://dx.doi.org/10.1371/journal.pone.0089919

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