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β-Lapachone Ameliorates Lipotoxic Cardiomyopathy in Acyl CoA Synthase Transgenic Mice

Lipotoxic cardiomyopathy is caused by myocardial lipid accumulation and often occurs in patients with diabetes and obesity. This study investigated the effects of β-lapachone (β-lap), a natural compound that activates Sirt1 through elevation of the intracellular NAD(+) level, on acyl CoA synthase (A...

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Detalles Bibliográficos
Autores principales:	Jeong, Moon Hee, Tran, Nguyen Khoi Song, Kwak, Tae Hwan, Park, Byung Keon, Lee, Chul Soon, Park, Tae-Sik, Lee, Young-Hoon, Park, Woo Jin, Yang, Dong Kwon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948739/ https://www.ncbi.nlm.nih.gov/pubmed/24614171 http://dx.doi.org/10.1371/journal.pone.0091039

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