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Detecting Structure of Haplotypes and Local Ancestry
We present a two-layer hidden Markov model to detect the structure of haplotypes for unrelated individuals. This allows us to model two scales of linkage disequilibrium (one within a group of haplotypes and one between groups), thereby taking advantage of rich haplotype information to infer local an...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Genetics Society of America
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948796/ https://www.ncbi.nlm.nih.gov/pubmed/24388880 http://dx.doi.org/10.1534/genetics.113.160697 |