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KSHV RTA Abolishes NFκB Responsive Gene Expression during Lytic Reactivation by Targeting vFLIP for Degradation via the Proteasome

Kaposi's sarcoma herpesvirus (KSHV) is a gamma-2 herpesvirus present in all cases of Kaposi's sarcoma, primary effusion lymphoma (PEL), and some cases of multicentric Castleman's disease. Viral FLICE inhibitory protein (vFLIP) is a latently expressed gene that has been shown to be ess...

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Detalles Bibliográficos
Autores principales:	Ehrlich, Elana S., Chmura, Jennifer C., Smith, John C., Kalu, Nene N., Hayward, Gary S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948842/ https://www.ncbi.nlm.nih.gov/pubmed/24614587 http://dx.doi.org/10.1371/journal.pone.0091359

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