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Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization

The effectiveness of current treatment for age related macular degeneration (AMD) by targeting one molecule is limited due to its multifactorial nature and heterogeneous pathologies. Treatment strategy to target multiple signaling pathways or pathological components in AMD pathogenesis is under inve...

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Detalles Bibliográficos
Autores principales:	Li, Y., Liu, X., Zhou, T., Kelley, M.R., Edwards, P., Gao, H., Qiao, X.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949093/ https://www.ncbi.nlm.nih.gov/pubmed/24624338 http://dx.doi.org/10.1016/j.redox.2014.01.023

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