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Polarized release of TCR-enriched microvesicles at the T cell immunological synapse

The recognition events that mediate adaptive cellular immunity and regulate antibody responses depend on intercellular contacts between T cells and antigen presenting cells (APC)(1). T cell signaling is initiated at these contacts when surface-expressed antigen receptors (TCR) recognize peptide frag...

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Detalles Bibliográficos
Autores principales: Choudhuri, Kaushik, Llodrá, Jaime, Roth, Eric W., Tsai, Jones, Gordo, Susana, Wucherpfennig, Kai W., Kam, Lance, Stokes, David L., Dustin, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949170/
https://www.ncbi.nlm.nih.gov/pubmed/24487619
http://dx.doi.org/10.1038/nature12951