Cargando…

Targeting TBP-Associated Factors in Ovarian Cancer

As ovarian tumors progress, they undergo a process of dedifferentiation, allowing adaptive changes in growth and morphology that promote metastasis and chemoresistance. Herein, we outline a hypothesis that TATA-box binding protein associated factors (TAFs), which compose the RNA Polymerase II initia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ribeiro, Jennifer R., Lovasco, Lindsay A., Vanderhyden, Barbara C., Freiman, Richard N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949196/ https://www.ncbi.nlm.nih.gov/pubmed/24653979 http://dx.doi.org/10.3389/fonc.2014.00045

Ejemplares similares

TBP2 is a substitute for TBP in Xenopus oocyte transcription
por: Akhtar, Waseem, et al.
Publicado: (2009)

Targeting Transcription Through Inhibition of TBP
por: Schug, Thaddeus T.
Publicado: (2011)

Activation of a T-box-Otx2-Gsc gene network independent of TBP and TBP-related factors
por: Gazdag, Emese, et al.
Publicado: (2016)

miR-93, miR-373, and miR-17-5p Negatively Regulate the Expression of TBP2 in Lung Cancer
por: Li, Ye, et al.
Publicado: (2020)

TBP-related factors: a paradigm of diversity in transcription initiation
por: Akhtar, Waseem, et al.
Publicado: (2011)

HAP1 can sequester a subset of TBP in cytoplasmic inclusions via specific interaction with the conserved TBP(CORE)
por: Prigge, Justin R, et al.
Publicado: (2007)

Evolutionary history of the TBP-domain superfamily
por: Brindefalk, Björn, et al.
Publicado: (2013)

A New Spontaneously Transformed Syngeneic Model of High-Grade Serous Ovarian Cancer with a Tumor-Initiating Cell Population
por: McCloskey, Curtis W., et al.
Publicado: (2014)

Sociodemographic disparities in targeted therapy in ovarian cancer in a national sample
por: Amin, Saber A., et al.
Publicado: (2023)

Mutational analysis of BTAF1–TBP interaction: BTAF1 can rescue DNA-binding defective TBP mutants
por: Klejman, Marcin P., et al.
Publicado: (2005)

RNA synthesis is associated with multiple TBP-chromatin binding events
por: Zaidi, Hussain A., et al.
Publicado: (2017)

Ovarian Cancer Targeted Theranostics
por: Nimmagadda, Sridhar, et al.
Publicado: (2020)

Animal models of ovarian cancer
por: Vanderhyden, Barbara C, et al.
Publicado: (2003)

TBP-Related Factor 2 as a Trigger for Robertsonian Translocations and Speciation
por: Cherezov, Roman O., et al.
Publicado: (2020)

Human Epididymis Protein 4 Promotes Events Associated with Metastatic Ovarian Cancer via Regulation of the Extracelluar Matrix
por: Ribeiro, Jennifer R., et al.
Publicado: (2018)

Immune Modeling Analysis Reveals Immunologic Signatures Associated With Improved Outcomes in High Grade Serous Ovarian Cancer
por: James, Nicole E., et al.
Publicado: (2021)

Affinity and competition for TBP are molecular determinants of gene expression noise
por: Ravarani, Charles N. J., et al.
Publicado: (2016)

aTBP: A versatile tool for fish genotyping
por: Gianì, Silvia, et al.
Publicado: (2020)

Beyond the Biomarker: Understanding the Diverse Roles of Human Epididymis Protein 4 in the Pathogenesis of Epithelial Ovarian Cancer
por: James, Nicole E., et al.
Publicado: (2018)

TBP2 is a general transcription factor specialized for female germ cells
por: Müller, Ferenc, et al.
Publicado: (2009)

TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells
por: Malecova, Barbora, et al.
Publicado: (2016)

TRF2, but not TBP, mediates the transcription of ribosomal protein genes
por: Wang, Yuan-Liang, et al.
Publicado: (2014)

A bioinformatic analysis of WFDC2 (HE4) expression in high grade serous ovarian cancer reveals tumor-specific changes in metabolic and extracellular matrix gene expression
por: James, Nicole E., et al.
Publicado: (2022)

The significance of ovarian fibrosis
por: Landry, David A., et al.
Publicado: (2020)

Targeting oxidative phosphorylation as an approach for the treatment of ovarian cancer
por: Wu, Yinjie, et al.
Publicado: (2022)

Editorial: Novel targets for ovarian cancer stem cells
por: Wang, Yinu, et al.
Publicado: (2023)

Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
por: Ravarani, Charles N. J., et al.
Publicado: (2020)

Conformational changes and catalytic inefficiency associated with Mot1-mediated TBP–DNA dissociation
por: Heiss, Gregor, et al.
Publicado: (2019)

A kinetic model of TBP auto-regulation exhibits bistability
por: Gokhale, Sucheta A, et al.
Publicado: (2010)

Same same but different: The evolution of TBP in archaea and their eukaryotic offspring
por: Blombach, Fabian, et al.
Publicado: (2017)

TXNIP/TBP-2: A Master Regulator for Glucose Homeostasis
por: Yoshihara, Eiji
Publicado: (2020)

MmeI: a minimal Type II restriction-modification system that only modifies one DNA strand for host protection
por: Morgan, Richard D., et al.
Publicado: (2008)

Histones and Their Modifications in Ovarian Cancer – Drivers of Disease and Therapeutic Targets
por: Marsh, Deborah J., et al.
Publicado: (2014)

Technical challenges and limitations of current mouse models of ovarian cancer
por: Garson, Kenneth, et al.
Publicado: (2012)

CHTOP in Chemoresistant Epithelial Ovarian Cancer: A Novel and Potential Therapeutic Target
por: Feng, Xiaojie, et al.
Publicado: (2019)

Large normal-range TBP and ATXN7 CAG repeat lengths are associated with increased lifetime risk of depression
por: Gardiner, S L, et al.
Publicado: (2017)

Deregulation of Lipid Metabolism: The Critical Factors in Ovarian Cancer
por: Ji, Zhaodong, et al.
Publicado: (2020)

Anti-Tumor and Anti-Invasive Effects of ONC201 on Ovarian Cancer Cells and a Transgenic Mouse Model of Serous Ovarian Cancer
por: Fan, Yali, et al.
Publicado: (2022)

PAX2 induces vascular-like structures in normal ovarian cells and ovarian cancer
por: Alwosaibai, Kholoud, et al.
Publicado: (2022)

Aberrant Cholesterol Metabolism in Ovarian Cancer: Identification of Novel Therapeutic Targets
por: He, Jiangnan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_262553t52sa2ug7tc5uud5k46n