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AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels
AMP-activated protein kinase appears to have evolved in single-celled eukaryotes as an adenine nucleotide sensor that maintains energy homeostasis at the cellular level. However, during evolution of more complex multicellular organisms, the system has adapted to interact with hormones so that it als...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Physiological Society
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949207/ https://www.ncbi.nlm.nih.gov/pubmed/24583766 http://dx.doi.org/10.1152/physiol.00050.2013 |
| _version_ | 1782306881685946368 |
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| author | Hardie, D. Grahame Ashford, Michael L. J. |
| author_facet | Hardie, D. Grahame Ashford, Michael L. J. |
| author_sort | Hardie, D. Grahame |
| collection | PubMed |
| description | AMP-activated protein kinase appears to have evolved in single-celled eukaryotes as an adenine nucleotide sensor that maintains energy homeostasis at the cellular level. However, during evolution of more complex multicellular organisms, the system has adapted to interact with hormones so that it also plays a key role in balancing energy intake and expenditure at the whole body level. |
| format | Online Article Text |
| id | pubmed-3949207 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | American Physiological Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-39492072014-08-06 AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels Hardie, D. Grahame Ashford, Michael L. J. Physiology (Bethesda) Reviews AMP-activated protein kinase appears to have evolved in single-celled eukaryotes as an adenine nucleotide sensor that maintains energy homeostasis at the cellular level. However, during evolution of more complex multicellular organisms, the system has adapted to interact with hormones so that it also plays a key role in balancing energy intake and expenditure at the whole body level. American Physiological Society 2014-03 /pmc/articles/PMC3949207/ /pubmed/24583766 http://dx.doi.org/10.1152/physiol.00050.2013 Text en ©2014 Int. Union Physiol. Sci./Am. Physiol. Soc. Licensed under Creative Commons Attribution CC-BY 3.0 (http://creativecommons.org/licenses/by/3.0/deed.en_US) : the American Physiological Society. |
| spellingShingle | Reviews Hardie, D. Grahame Ashford, Michael L. J. AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels |
| title | AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels |
| title_full | AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels |
| title_fullStr | AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels |
| title_full_unstemmed | AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels |
| title_short | AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels |
| title_sort | ampk: regulating energy balance at the cellular and whole body levels |
| topic | Reviews |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949207/ https://www.ncbi.nlm.nih.gov/pubmed/24583766 http://dx.doi.org/10.1152/physiol.00050.2013 |
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