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Direct Detection of a Sulfonate Ester Genotoxic Impurity by Atmospheric-Pressure Thermal Desorption–Extractive Electrospray–Mass Spectrometry

[Image: see text] A direct, ambient ionization method has been developed using atmospheric pressure thermal desorption–extractive electrospray–mass spectrometry (AP/TD-EESI-MS) for the detection of the genotoxic impurity (GTI) methyl p-toluenesulfonate (MTS) in a surrogate pharmaceutical matrix. A c...

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Detalles Bibliográficos
Autores principales:	Devenport, Neil A., Sealey, Laura C., Alruways, Faisal H., Weston, Daniel J., Reynolds, James C., Creaser, Colin S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2013
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949410/ https://www.ncbi.nlm.nih.gov/pubmed/23750985 http://dx.doi.org/10.1021/ac401054n

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