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Identification of both GABA(A) receptors and voltage-activated Na(+) channels as molecular targets of anticonvulsant α-asarone

Alpha (α)-asarone, a major effective component isolated from the Chinese medicinal herb Acorus tatarinowii, is clinically used as medication for treating epilepsy, cough, bronchitis, and asthma. In the present study, we demonstrated that α-asarone targets central nervous system GABA(A) receptor as w...

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Detalles Bibliográficos
Autores principales: Wang, Ze-Jun, Levinson, Simon R., Sun, Liqin, Heinbockel, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949418/
https://www.ncbi.nlm.nih.gov/pubmed/24653701
http://dx.doi.org/10.3389/fphar.2014.00040