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Controlled release of nerve growth factor from heparin-conjugated fibrin gel within the nerve growth factor-delivering implant
OBJECTIVES: Although nerve growth factor (NGF) could promote the functional regeneration of an injured peripheral nerve, it is very difficult for NGF to sustain the therapeutic dose in the defect due to its short half-life. In this study, we loaded the NGF-bound heparin-conjugated fibrin (HCF) gel i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Association of Oral and Maxillofacial Surgeons
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949490/ https://www.ncbi.nlm.nih.gov/pubmed/24627836 http://dx.doi.org/10.5125/jkaoms.2014.40.1.3 |