Cargando…

Epitope-specific antibody response is controlled by immunoglobulin V(H) polymorphisms

Autoantibody formation is essential for the development of certain autoimmune diseases like rheumatoid arthritis (RA). Anti-type II collagen (CII) antibodies are found in RA patients; they interact with cartilage in vivo and are often highly pathogenic in the mouse. Autoreactivity to CII is directed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Raposo, Bruno, Dobritzsch, Doreen, Ge, Changrong, Ekman, Diana, Xu, Bingze, Lindh, Ingrid, Förster, Michael, Uysal, Hüseyin, Nandakumar, Kutty Selva, Schneider, Gunter, Holmdahl, Rikard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949579/ https://www.ncbi.nlm.nih.gov/pubmed/24534192 http://dx.doi.org/10.1084/jem.20130968

Ejemplares similares

Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice
por: Lindh, Ingrid, et al.
Publicado: (2014)

Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor
por: Ge, Changrong, et al.
Publicado: (2022)

A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis
por: Nandakumar, Kutty Selva, et al.
Publicado: (2010)

Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis
por: Nandakumar, Kutty Selva, et al.
Publicado: (2006)

Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis
por: Li, Yanpeng, et al.
Publicado: (2020)

Correction: A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis
por: Nandakumar, Kutty Selva, et al.
Publicado: (2011)

Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity
por: Carlsen, Stefan, et al.
Publicado: (2006)

Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen
por: Bajtner, Estelle, et al.
Publicado: (2005)

Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells
por: Nandakumar, Kutty Selva, et al.
Publicado: (2004)

Human NCF1(90H) Variant Promotes IL-23/IL-17—Dependent Mannan-Induced Psoriasis and Psoriatic Arthritis
por: Li, Yanpeng, et al.
Publicado: (2023)

A Shared Epitope of Collagen Type XI and Type II Is Recognized by Pathogenic Antibodies in Mice and Humans with Arthritis
por: Tong, Dongmei, et al.
Publicado: (2018)

Cartilage Oligomeric Matrix Protein Induced Arthritis—A New Model for Rheumatoid Arthritis in the C57BL/6 Mouse
por: Zhao, Yunjuan, et al.
Publicado: (2021)

Cartilage oligomeric matrix protein specific antibodies are pathogenic
por: Geng, Hui, et al.
Publicado: (2012)

Genetic dissection of a major haplotype associated with arthritis reveal FcγR2b and FcγR3 to act additively
por: Vaartjes, Daniëlle, et al.
Publicado: (2020)

Antibodies to Cartilage Oligomeric Matrix Protein Are Pathogenic in Mice and May Be Clinically Relevant in Rheumatoid Arthritis
por: Ge, Changrong, et al.
Publicado: (2022)

Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development
por: Bäcklund, Alexandra, et al.
Publicado: (2011)

Polymorphic estrogen receptor binding site causes Cd2-dependent sex bias in the susceptibility to autoimmune diseases
por: Fernandez Lahore, Gonzalo, et al.
Publicado: (2021)

Streptococcal Endo-β-N-Acetylglucosaminidase Suppresses Antibody-Mediated Inflammation In Vivo
por: Nandakumar, Kutty Selva, et al.
Publicado: (2018)

Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis
por: Geng, Hui, et al.
Publicado: (2008)

Characterization of chronic relapsing antibody mediated arthritis in mice with a mutation in Ncf1 causing reduced oxidative burst
por: Liang, Peibin, et al.
Publicado: (2022)

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis
por: Uysal, Hüseyin, et al.
Publicado: (2009)

DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions
por: Saribasak, Huseyin, et al.
Publicado: (2012)

Modulation of granulocyte-endothelium interactions by antileukoproteinase: inhibition of anti-type II collagen antibody-induced leukocyte attachment to the synovial endothelium
por: Sehnert, Bettina, et al.
Publicado: (2006)

Platelets derived citrullinated proteins and microparticles are potential autoantibodies ACPA targets in RA patients
por: Xu, Minjie, et al.
Publicado: (2023)

Comparative analysis of collagen type II-specific immune responses during development of collagen-induced arthritis in two B10 mouse strains
por: Batsalova, Tsvetelina, et al.
Publicado: (2012)

CELL SURFACE IMMUNOGLOBULIN : VIII. SYNTHESIS, SECRETION, AND CELL SURFACE EXPRESSION OF IMMUNOGLOBULIN IN MURINE THORACIC DUCT LYMPHOCYTES
por: Uhr, Jonathan W., et al.
Publicado: (1974)

THE STRUCTURAL BASIS FOR BINDING OF COMPLEMENT BY IMMUNOGLOBULIN M
por: Hurst, Mary M., et al.
Publicado: (1974)

Immunoglobulin E plays an immunoregulatory role in lupus
por: Dema, Barbara, et al.
Publicado: (2014)

Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues
por: Nandakumar, Kutty Selva
Publicado: (2018)

Vaccines and Vaccine Adjuvants for Infectious Diseases and Autoimmune Diseases
por: Nandakumar, Kutty Selva
Publicado: (2023)

Rheumatoid arthritis sera antibodies to citrullinated collagen type II bind to joint cartilage
por: Li, Qixing, et al.
Publicado: (2022)

The cohesin complex regulates immunoglobulin class switch recombination
por: Thomas-Claudepierre, Anne-Sophie, et al.
Publicado: (2013)

Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro
por: Crombie, Duncan E, et al.
Publicado: (2005)

CHARACTERIZATION OF CYSTIC FIBROSIS FACTOR AND ITS INTERACTION WITH HUMAN IMMUNOGLOBULIN
por: Danes, B. Shannon, et al.
Publicado: (1973)

Contribution of DNA polymerase η to immunoglobulin gene hypermutation in the mouse
por: Delbos, Frédéric, et al.
Publicado: (2005)

Targeting Mucosal Sites by Polymeric Immunoglobulin Receptor-directed Peptides
por: White, Kendra D., et al.
Publicado: (2002)

The insulin A-chain epitope recognized by human T cells is posttranslationally modified
por: Mannering, Stuart I., et al.
Publicado: (2005)

VARIATION IN ACCESSIBLE CELL SURFACE IMMUNOGLOBULIN AMONG ANTIBODY-FORMING CELLS
por: Nossal, G. J. V., et al.
Publicado: (1972)

Deficiency in Serum Immunoglobulin (Ig)m Predisposes to Development of Igg Autoantibodies
por: Ehrenstein, Michael R., et al.
Publicado: (2000)

Human PMS2 deficiency is associated with impaired immunoglobulin class switch recombination
por: Péron, Sophie, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_82kv6jpfruf82ie21bemrm4t3c