Brain Endothelial Cells Control Fertility through Ovarian-Steroid–Dependent Release of Semaphorin 3A

Neuropilin-1 (Nrp1) guides the development of the nervous and vascular systems, but its role in the mature brain remains to be explored. Here we report that the expression of the 65 kDa isoform of Sema3A, the ligand of Nrp1, by adult vascular endothelial cells, is regulated during the ovarian cycle...

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Detalles Bibliográficos
Autores principales: Giacobini, Paolo, Parkash, Jyoti, Campagne, Céline, Messina, Andrea, Casoni, Filippo, Vanacker, Charlotte, Langlet, Fanny, Hobo, Barbara, Cagnoni, Gabriella, Gallet, Sarah, Hanchate, Naresh Kumar, Mazur, Danièle, Taniguchi, Masahiko, Mazzone, Massimiliano, Verhaagen, Joost, Ciofi, Philippe, Bouret, Sébastien G., Tamagnone, Luca, Prevot, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949669/
https://www.ncbi.nlm.nih.gov/pubmed/24618750
http://dx.doi.org/10.1371/journal.pbio.1001808

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