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Calycosin Suppresses Breast Cancer Cell Growth via ERβ-Dependent Regulation of IGF-1R, p38 MAPK and PI3K/Akt Pathways

We previously reported that calycosin, a natural phytoestrogen structurally similar to estrogen, successfully triggered apoptosis of estrogen receptor (ER)-positive breast cancer cell line, MCF-7. To better understand the antitumor activities of calycosin against breast cancer, besides MCF-7 cells,...

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Detalles Bibliográficos
Autores principales: Chen, Jian, Hou, Ruanling, Zhang, Xing, Ye, Yu, Wang, Yong, Tian, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949755/
https://www.ncbi.nlm.nih.gov/pubmed/24618835
http://dx.doi.org/10.1371/journal.pone.0091245