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Molecular Mechanisms Underlying the Enhanced Analgesic Effect of Oxycodone Compared to Morphine in Chemotherapy-Induced Neuropathic Pain

Oxycodone is a μ-opioid receptor agonist, used for the treatment of a large variety of painful disorders. Several studies have reported that oxycodone is a more potent pain reliever than morphine, and that it improves the quality of life of patients. However, the neurobiological mechanisms underlyin...

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Detalles Bibliográficos
Autores principales: Thibault, Karine, Calvino, Bernard, Rivals, Isabelle, Marchand, Fabien, Dubacq, Sophie, McMahon, Stephen B., Pezet, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949760/
https://www.ncbi.nlm.nih.gov/pubmed/24618941
http://dx.doi.org/10.1371/journal.pone.0091297