Constitutive Activation of IKK2/NF-κB Impairs Osteogenesis and Skeletal Development

Pathologic conditions impair bone homeostasis. The transcription factor NF-κB regulates bone homeostasis and is central to bone pathologies. Whereas contribution of NF-κB to heightened osteoclast activity is well-documented, the mechanisms underlying NF-κB impact on chondrocytes and osteoblasts are...

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Detalles Bibliográficos
Autores principales: Swarnkar, Gaurav, Zhang, Kaihua, Mbalaviele, Gabriel, Long, Fanxin, Abu-Amer, Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949987/
https://www.ncbi.nlm.nih.gov/pubmed/24618907
http://dx.doi.org/10.1371/journal.pone.0091421

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