Cargando…
Epigenetic Silencing of Apoptosis-Inducing Gene Expression Can Be Efficiently Overcome by Combined SAHA and TRAIL Treatment in Uterine Sarcoma Cells
The lack of knowledge about molecular pathology of uterine sarcomas with a representation of 3–7% of all malignant uterine tumors prevents the establishment of effective therapy protocols. Here, we explored advanced therapeutic options to the previously discovered antitumorigenic effects of the hist...
Autores principales: | Fröhlich, Leopold F., Mrakovcic, Maria, Smole, Claudia, Lahiri, Pooja, Zatloukal, Kurt |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950220/ https://www.ncbi.nlm.nih.gov/pubmed/24618889 http://dx.doi.org/10.1371/journal.pone.0091558 |
Ejemplares similares
-
Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway
por: Fröhlich, Leopold F., et al.
Publicado: (2016) -
p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies
por: Lahiri, Pooja, et al.
Publicado: (2016) -
SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma
por: Crawford, N, et al.
Publicado: (2013) -
Assessment of Long-Term Effects of Nanoparticles in a Microcarrier Cell Culture System
por: Mrakovcic, Maria, et al.
Publicado: (2013) -
Epigenetic Targeting of Autophagy via HDAC Inhibition in Tumor Cells: Role of p53
por: Mrakovcic, Maria, et al.
Publicado: (2018)