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Epigenetic Silencing of Apoptosis-Inducing Gene Expression Can Be Efficiently Overcome by Combined SAHA and TRAIL Treatment in Uterine Sarcoma Cells

The lack of knowledge about molecular pathology of uterine sarcomas with a representation of 3–7% of all malignant uterine tumors prevents the establishment of effective therapy protocols. Here, we explored advanced therapeutic options to the previously discovered antitumorigenic effects of the hist...

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Detalles Bibliográficos
Autores principales: Fröhlich, Leopold F., Mrakovcic, Maria, Smole, Claudia, Lahiri, Pooja, Zatloukal, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950220/
https://www.ncbi.nlm.nih.gov/pubmed/24618889
http://dx.doi.org/10.1371/journal.pone.0091558

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