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Susceptibility of Different Hepatitis B Virus Isolates to Interferon-Alpha in a Mouse Model Based on Hydrodynamic Injection

Interferon alpha (IFN-α) is commonly used for the treatment of chronic hepatitis B (CHB) patients. Many factors including viral genetics may determine the outcome of IFN-α therapy. In this study, we tested whether the expression of IFN-α directly in the liver inhibits HBV gene expression and replica...

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Detalles Bibliográficos
Autores principales:	Song, Jingjiao, Zhou, Yun, Li, Sheng, Wang, Baoju, Zheng, Xin, Wu, Jun, Gibbert, Kathrin, Dittmer, Ulf, Lu, Mengji, Yang, Dongliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950299/ https://www.ncbi.nlm.nih.gov/pubmed/24618716 http://dx.doi.org/10.1371/journal.pone.0090977

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