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A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis
Despite recent progress, the physiological role of Hippo signaling in mammary gland development and tumorigenesis remains poorly understood. Here we show that the Hippo pathway is functionally dispensable in virgin mammary glands but specifically required during pregnancy. In contrast to many other...
Autores principales: | Chen, Qian, Zhang, Nailing, Gray, Ryan S., Li, Huili, Ewald, Andrew J., Zahnow, Cynthia A., Pan, Duojia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950341/ https://www.ncbi.nlm.nih.gov/pubmed/24589775 http://dx.doi.org/10.1101/gad.233676.113 |
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