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Conserved residues in yeast initiator tRNA calibrate initiation accuracy by regulating preinitiation complex stability at the start codon

Eukaryotic initiator tRNA (tRNA(i)) contains several highly conserved unique sequence features, but their importance in accurate start codon selection was unknown. Here we show that conserved bases throughout tRNA(i), from the anticodon stem to acceptor stem, play key roles in ensuring the fidelity...

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Detalles Bibliográficos
Autores principales:	Dong, Jinsheng, Munoz, Antonio, Kolitz, Sarah E., Saini, Adesh K., Chiu, Wen-ling, Rahman, Hafsa, Lorsch, Jon R., Hinnebusch, Alan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950347/ https://www.ncbi.nlm.nih.gov/pubmed/24589778 http://dx.doi.org/10.1101/gad.236547.113

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