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Structural basis for promoter specificity switching of RNA polymerase by a phage factor
Transcription of DNA to RNA by DNA-dependent RNA polymerase (RNAP) is the first step of gene expression and a major regulation point. Bacteriophages hijack their host's transcription machinery and direct it to serve their needs. The gp39 protein encoded by Thermus thermophilus phage P23-45 bind...
Autores principales: | Tagami, Shunsuke, Sekine, Shun-ichi, Minakhin, Leonid, Esyunina, Daria, Akasaka, Ryogo, Shirouzu, Mikako, Kulbachinskiy, Andrey, Severinov, Konstantin, Yokoyama, Shigeyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950348/ https://www.ncbi.nlm.nih.gov/pubmed/24589779 http://dx.doi.org/10.1101/gad.233916.113 |
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