Estrogen Receptor Antagonists Are Anti-Cryptococcal Agents That Directly Bind EF Hand Proteins and Synergize with Fluconazole In Vivo

Cryptococcosis is an infectious disease of global significance for which new therapies are needed. Repurposing previously developed drugs for new indications can expedite the translation of new therapies from bench to beside. Here, we characterized the anti-cryptococcal activity and antifungal mecha...

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Detalles Bibliográficos
Autores principales: Butts, Arielle, Koselny, Kristy, Chabrier-Roselló, Yeissa, Semighini, Camile P., Brown, Jessica C. S., Wang, Xuying, Annadurai, Sivakumar, DiDone, Louis, Tabroff, Julie, Childers, Wayne E., Abou-Gharbia, Magid, Wellington, Melanie, Cardenas, Maria E., Madhani, Hiten D., Heitman, Joseph, Krysan, Damian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950514/
https://www.ncbi.nlm.nih.gov/pubmed/24520056
http://dx.doi.org/10.1128/mBio.00765-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950514/
https://www.ncbi.nlm.nih.gov/pubmed/24520056
http://dx.doi.org/10.1128/mBio.00765-13

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