Genome-Wide Saturation Mutagenesis of Burkholderia pseudomallei K96243 Predicts Essential Genes and Novel Targets for Antimicrobial Development

Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infectious disease for which there is no vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its natural resistance to most antibiotics, the development of n...

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Detalles Bibliográficos
Autores principales: Moule, Madeleine G., Hemsley, Claudia M., Seet, Qihui, Guerra-Assunção, José Afonso, Lim, Jiali, Sarkar-Tyson, Mitali, Clark, Taane G., Tan, Patrick B. O., Titball, Richard W., Cuccui, Jon, Wren, Brendan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950516/
https://www.ncbi.nlm.nih.gov/pubmed/24520057
http://dx.doi.org/10.1128/mBio.00926-13

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