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Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae
The cytosolic N-acetylmuramoyl-l-alanine amidase LytA protein of Streptococcus pneumoniae, which is released by bacterial lysis, associates with the cell wall via its choline-binding motif. During exponential growth, LytA accesses its peptidoglycan substrate to cause lysis only when nascent peptidog...
Autores principales: | Mellroth, Peter, Sandalova, Tatyana, Kikhney, Alexey, Vilaplana, Francisco, Hesek, Dusan, Lee, Mijoon, Mobashery, Shahriar, Normark, Staffan, Svergun, Dmitri, Henriques-Normark, Birgitta, Achour, Adnane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950521/ https://www.ncbi.nlm.nih.gov/pubmed/24520066 http://dx.doi.org/10.1128/mBio.01120-13 |
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