Frequency and Prognostic Relevance of FLT3 Mutations in Saudi Acute Myeloid Leukemia Patients

The Fms-like tyrosine kinase-3 (FLT3) is a receptor tyrosine kinase that plays a key role in cell survival, proliferation, and differentiation of hematopoietic stem cells. Mutations of FLT3 were first described in 1997 and account for the most frequent molecular mutations in acute myeloid leukemia (...

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Detalles Bibliográficos
Autores principales: Elyamany, Ghaleb, Awad, Mohammad, Fadalla, Kamal, Albalawi, Mohamed, Al Shahrani, Mohammad, Al Abdulaaly, Abdulaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950551/
https://www.ncbi.nlm.nih.gov/pubmed/24696688
http://dx.doi.org/10.1155/2014/141360

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