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Basal PIR expression in HeLa cells is driven by NRF2 via evolutionary conserved antioxidant response element

Pirin, a product of the PIR gene, is an iron-binding protein acting as a transcriptional coregulator implicated in the regulation of the NF-κB-related transcription via interaction with RelA (p65), as well as BCL3 and NF-κB1 (p50) proteins. Alterations in pirin expression were observed in various tu...

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Detalles Bibliográficos
Autores principales: Brzóska, Kamil, Stępkowski, Tomasz M., Kruszewski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950616/
https://www.ncbi.nlm.nih.gov/pubmed/24390086
http://dx.doi.org/10.1007/s11010-013-1931-0