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High-density lipoprotein induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through sphingosine kinase-2

High-density lipoprotein (HDL) has a significant cardioprotective effects. HDL induces cyclooxygenase-2 (COX-2) expression and prostacyclin I-2 (PGI-2) release in vascular endothelial cells, which contributes to its anti-atherogenic effects. However, the underlying mechanisms are not fully understoo...

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Detalles Bibliográficos
Autores principales: Xiong, Sheng-Lin, Liu, Xing, Yi, Guang-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950625/
https://www.ncbi.nlm.nih.gov/pubmed/24385109
http://dx.doi.org/10.1007/s11010-013-1941-y