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The Fusion Protein of CTP-HBcAg18-27-Tapasin Mediates the Apoptosis of CD8(+)T Cells and CD8(+) T Cell Response in HLA-A2 Transgenic Mice
BACKGROUND: HBV-specific cytotoxic T lymphocyte (CTL) activity is believed to play a critical role in controlling HBV infection. The phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway manipulates cell fate decisions in many different cell types by regulating the activity of downstream effect...
Autores principales: | Tang, Yu-Yan, Tang, Zheng-Hao, Zhang, Yi, Zhuo, Meng, Zang, Guo-Qing, Chen, Xiao-Hua, Yu, Yong-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950630/ https://www.ncbi.nlm.nih.gov/pubmed/24693311 http://dx.doi.org/10.5812/hepatmon.16161 |
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