Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing

A key player in translation initiation is eIF4E, the mRNA 5′ cap-binding protein. 4E-Transporter (4E-T) is a recently characterized eIF4E-binding protein, which regulates specific mRNAs in several developmental model systems. Here, we first investigated the role of its enrichment in P-bodies and eIF...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamenska, Anastasiia, Lu, Wei-Ting, Kubacka, Dorota, Broomhead, Helen, Minshall, Nicola, Bushell, Martin, Standart, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950672/
https://www.ncbi.nlm.nih.gov/pubmed/24335285
http://dx.doi.org/10.1093/nar/gkt1265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950672/
https://www.ncbi.nlm.nih.gov/pubmed/24335285
http://dx.doi.org/10.1093/nar/gkt1265

Ejemplares similares