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Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing
A key player in translation initiation is eIF4E, the mRNA 5′ cap-binding protein. 4E-Transporter (4E-T) is a recently characterized eIF4E-binding protein, which regulates specific mRNAs in several developmental model systems. Here, we first investigated the role of its enrichment in P-bodies and eIF...
Autores principales: | Kamenska, Anastasiia, Lu, Wei-Ting, Kubacka, Dorota, Broomhead, Helen, Minshall, Nicola, Bushell, Martin, Standart, Nancy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950672/ https://www.ncbi.nlm.nih.gov/pubmed/24335285 http://dx.doi.org/10.1093/nar/gkt1265 |
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